| DSS | Dejerine-Sottas Syndrome |
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| Sottas, Jules | <person> French neurologist, 1866-1943. See: Dejerine-Sottas disease. (05 Mar 2000) |
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| Dejerine-Sottas disease | A familial type of demyelinating sensorimotor polyneuropathy that begins in early childhood and is slowly progressive; clinically characterised by foot pain and paresthesias, followed by symmetrical weakness and wasting of the distal limbs; one of the causes of stork legs; patients are wheelchair bound at an early age; peripheral nerves are palpably enlarged and non-tender; pathologically, onion bulb formation is seen in the nerves: whorls of overlapping, intertwined Schwann cell processes that encircle bare axons; usually autosomal recessive inheritance. Synonym: Dejerine's disease, progressive hypertrophic polyneuropathy. (05 Mar 2000) |
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