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  • promoter gene
    ÇÁ·Î¸ðÅÍ À¯ÀüÀÚ(ë¶îîí­)
  • promoter mutation
    ÇÁ·Î¸ðÅÍ º¯ÀÌ(ܨì¶)
  • promoter strength
    ÇÁ·Î¸ðÅÍ °­µµ(Ë­Óø)
  • promoter-down mutation
    ÇÁ·Î¸ðÅÍ ±â´ÉÀúÇÏ º¯ÀÌ(ѦÒöî¸ù»Ü¨ì¶)
  • promoter-up mutation
    ÇÁ·Î¸ðÅÍ ±â´É»ó½Âº¯ÀÌ(ѦÒöß¾ã°Ü¨ì¶)
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promoter <molecular biology> A region of DNA to which RNA polymerase binds before initiating the transcription of DNA into RNA.
The nucleotide at which transcription starts is designated +1 and nucleotides are numbered from this with negative numbers indicating upstream nucleotides and positive downstream nucleotides.
most bacterial promoters contain two consensus sequences that seem to be essential for the binding of the polymerase. The first, the Pribnow box, is at about 10 and has the consensus sequence 5' TATAAT 3'. The second, the 35 sequence, is centred about 35 and has the consensus sequence 5' TTGACA 3'.
most factors that regulate gene transcription do so by binding at or near the promoter and affecting the initiation of transcription. Much less is known about eukaryote promoters, each of the three RNA polymerases has a different promoter.
RNA polymerase I recognises a single promoter for the precursor of rRNA.
RNA polymerase II, that transcribes all genes coding for polypeptides, recognises many thousands of promoters. most have the Goldberg Hogness or TATA box that is centred around position 25 and has the consensus sequence 5' TATAAAA 3'. Several promoters have a CAAT box around 90 with the consensus sequence 5' GGCCAATCT 3'. There is increasing evidence that all promoters for housekeeping genes contain multiple copies of a GC rich element that includes the sequence 5' GGGCGG 3'. Transcription by polymerase II is also affected by more distant elements known as enhancers.
RNA polymerase III synthesises 5s ribosomal RNA, all tRNAs and a number of small RNAs. The promoter for RNA polymerase III is located within the gene either as a single sequence, as in the 5s RNA gene or as two blocks, as in all tRNA genes.
(13 Nov 1997)
promoter insertion <molecular biology> Activation of a gene by the nearby integration of a virus. The long-terminal repeat acts as a promoter for the host gene. A form of insertional mutagenesis.
(18 Nov 1997)
promoter regions <genetics> DNA sequences which are recognised (directly or indirectly) and bound by a DNA-dependent RNA polymerase during the initiation of transcription. Highly conserved sequences within the promoter include the pribnow box in bacteria and the tata box in eukaryotes.
(12 Dec 1998)
MeSH(Medical Subject Headings) ¸ÂÃã °Ë»ö (http://www.nlm.nih.gov) °á°ú : 1 ÆäÀÌÁö: 1
  • Promoter Regions (Genetics) - »õâ DNA sequences which are recognized (directly or indirectly) and bound by a DNA-dependent RNA polymerase during the initiation of transcription. Highly conserved sequences within the promoter include the Pribnow box in bacteria and the TATA BOX in eukaryotes.
    Synonyms : Promoter, Promoter Regions, Promotor, Promotor (Genetics), Promotor Regions, Promotor Regions (Genetics), Pseudopromoter, Early Promoter, Late Promoter, Middle Promoter, Promoter Region, Promoter Region (Genetics), Promoter, Early, Promoter, Late, Promoter, Middle
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promoter someone who is an active supporter and advocate showman: a sponsor who books and stages public entertainments
Ãâó: wordnet.princeton.edu/perl/webwn
promoter A region of DNA, usually upstream of a coding sequence, that binds RNA polymerase and directs the enzyme to the correct transcriptional start site. (10)
Ãâó: ppathw3.cals.cornell.edu/glossary/Defs_P.htm
promoter A region of DNA involved in binding of RNA polymerase to initiate transcription.
Ãâó: depts.washington.edu/~genetics/courses/genet372/w2...
promoter a nucleotide sequence in a gene to which RNA polymerase attaches in order to begin transcription of mRNA.
Ãâó: www.mycolog.com/GLOSSARY.htm
promoter A regulatory segment of DNA immediately upstream and adjacent to a gene, which provides a binding site for RNA Polymerase to allow transcription of the adjacent downstream gene.
Ãâó: www.lsdn.com/glance_glossary.shtml
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  • promote
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Promote make publicity for
Promote board games: change a chess pawn for a king by advancing it to the eighth row, or change a checker piece for a more valuable piece by moving it the row closest to your opponent
Promote board games: be changed for a superior chess or checker piece
Promote give a promotion to or assign to a higher position
Promote contribute to the progress or growth of
Promote someone who is an active supporter and advocate
Promote a sponsor who books and stages public entertainments
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