| oncogen | <oncology, pharmacology> Synonym for carcinogen, an agent causing cancer. (18 Nov 1997) |
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| oncogene | <molecular biology, oncology> Mutated and/or overexpressed version of a normal gene of animal cells (the proto-oncogene) that in a dominant fashion can release the cell from normal restraints on growth and thus alone or in concert with other changes, convert a cell into a tumour cell. (18 Nov 1997) |
| oncogene protein gp140(v-fms) | Transforming glycoprotein coded by the fms oncogene from the susan mcdonough strain of feline sarcoma virus (sm-fesv). The oncogene protein v-fms lacks sequences, which, in the highly homologous proto-oncogene protein c-fms (csf-1 receptor), normally serve to regulate its tyrosine kinase activity. The missing sequences in v-fms mimic the effect of ligand and lead to constitutive cell growth. The protein gp120(v-fms) is post-translationally modified to generate gp140(v-fms). (12 Dec 1998) |
| oncogene protein p21(ras) | Transforming protein encoded by ras oncogenes. Point mutations in the cellular ras gene (c-ras) can also result in a mutant p21 protein that can transform mammalian cells. Oncogene protein p21(ras) has been directly implicated in human neoplasms, perhaps accounting for as much as 15-20% of all human tumours. (12 Dec 1998) |
| oncogene protein p55(v-myc) | Transforming protein coded by myc oncogenes. The v-myc protein has been found in several replication-defective avian retrovirus isolates which induce a broad spectrum of malignancies. (12 Dec 1998) |
| oncogene protein p65(gag-jun) | Transforming protein coded by jun oncogenes (genes, jun). This is a gag-onc fusion protein of about 65 kD derived from avian sarcoma virus. V-jun lacks a negative regulatory domain that regulates transcription in c-jun. (12 Dec 1998) |
| oncogene protein pp60(v-src) | <chemical> Tyrosine-specific protein kinase encoded by the v-src oncogene of rous sarcoma virus. The transforming activity of pp60(v-src) depends on both the lack of a critical carboxy-terminal tyrosine phosphorylation site at position 527, and the attachment of pp60(v-src) to the plasma membrane which is accomplished by myristylation of its n-terminal glycine. Chemical name: Kinase (phosphorylating), protein pp60src (12 Dec 1998) |
| oncogene proteins | Proteins coded by oncogenes. They include proteins resulting from the fusion of an oncogene and another gene (oncogene proteins, fusion). (12 Dec 1998) |
| oncogene proteins v-abl | Transforming proteins encoded by the abl oncogenes. Oncogenic transformation of c-abl to v-abl occurs by insertional activation that results in deletions of specific n-terminal amino acids. (12 Dec 1998) |
| oncogene proteins v-erba | Transforming proteins encoded by erba oncogenes from the avian erythroblastosis virus. They are truncated versions of c-erba, the thyroid hormone receptor (receptors, thyroid hormone) that have retained both the DNA-binding and hormone-binding domains. Mutations in the hormone-binding domains abolish the transcriptional activation function. V-erba acts as a dominant repressor of c-erba, inducing transformation by disinhibiting proliferation. (12 Dec 1998) |
| oncogene proteins v-erbb | Transforming proteins encoded by erbb oncogenes from the avian erythroblastosis virus. The protein is a truncated form of the egf receptor (receptors, epidermal growth factor-urogastrone) whose kinase domain is constitutively activated by deletion of the ligand-binding domain. (12 Dec 1998) |
| oncogene proteins v-fos | Transforming proteins coded by fos oncogenes. These proteins have been found in the finkel-biskis-jinkins (fbj-msv) and finkel-biskis-reilly (fbr-msv) murine sarcoma viruses which induce osteogenic sarcomas in mice. The fbj-msv v-fos gene encodes a p55 kD protein and the fbr-msv v-fos gene encodes a p75 kD fusion protein. (12 Dec 1998) |
| oncogene proteins v-mos | Transforming proteins coded by mos oncogenes. The v-mos proteins were originally isolated from the moloney murine sarcoma virus (mo-msv). (12 Dec 1998) |
| oncogene proteins, fusion | The translation products of the fusion between an oncogene and another gene. The latter may be of viral or cellular origin. (12 Dec 1998) |
| oncogene proteins, viral | Products of viral oncogenes, most commonly retroviral oncogenes. They usually have transforming and often protein kinase activities. (12 Dec 1998) |
Synonyms : Oncogene Fusions
Synonyms : fms Oncogene Product gp120, fms Oncogene Product gp140, gp120 v-fms, gp140 v-fms, gp120 v fms, gp140 v fms, v fms Protein, v-fms, gp120, v-fms, gp140
Synonyms : p21 Transforming Viral Protein, p21 v-H-ras, p21 v-Ha-ras, p21 v-Ki-ras, p21 v-ras, p21(v-H-ras), p21(v-K-ras), ras Oncogene Product p21, ras Oncogene p21 Product, p21 v H ras, p21 v Ha ras, p21 v Ki ras, p21 v ras, v-H-ras, p21, v-Ha-ras, p21, v-Ki-ras, p21
Synonyms : Oncogene Product p55(v-myc), myc Oncogene Product p55, p55 v-myc, Protein p55, v-myc, p55 v myc, v myc Protein p55
Synonyms : Oncogene Product v-jun, Oncogene Protein jun, p65 gag-jun, Fusion Proteins, gag jun, Oncogene Product v jun, Oncogene Protein v jun, Oncogene Protein, jun, Product v-jun, Oncogene, Protein jun, Oncogene, Protein v-jun, Oncogene, Protein, jun Oncogene, p65 gag jun
| oncogene |
a gene that causes normal cells to change into cancerous tumor cells
출처: wordnet.princeton.edu/perl/webwn
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| oncogenic osteomalacia |
oncogenous osteomalacia, osteomalacia occurring in association with usually benign mesenchymal neoplasms. The tumors appear to produce a substance that impairs renal tubular functions such as phosphate transport and hydroxylation of 25-hydroxyvitamin D; hypophosphatemia secondary to reduced renal resorption of phosphate is a major cause of the bone disease.
출처: www.mercksource.com/pp/us/cns/cns_hl_dorlands.jspz...
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| oncogenic |
an event or a cause that induces cancer.
출처: www.geocities.com/HotSprings/3982/dictionary.html
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| oncogene |
A gene that normally directs cell growth. If altered, an oncogene can promote or allow the uncontrolled growth of cancer. Alterations can be inherited or caused by an environmental exposure to carcinogens.
출처: www.stjude.org/glossary
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| oncogene |
A gene that causes cells to grow in an uncontrolled manner, ie, that causes cancer. Oncogenes are mutant forms of normal functional genes (called proto-oncogenes) that have a role in normal cell proliferation. Oncogenes are found in tumours and in retroviruses; in the latter case, having been picked up along with retroviral genes during retroviral replication in the host. ...
출처: www.fao.org/docrep/003/X3910E/X3910E18.htm
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| oncogen | a gene that causes normal cells to change into cancerous tumor cells |
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제품명 |
판매사 |
보험코드 | 성분/함량 | 구분/보험급여 |
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제품명 |
판매사 |
보험코드 | 성분/함량 | 구분/보험급여 |
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