| LESD | Letterer-Siwe disease |
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| L-S | Letterer-Siwe [disease] |
| Letterer, Erich | <person> German pathologist, *1895. See: Letterer-Siwe disease. (05 Mar 2000) |
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| letterer-siwe disease | A condition marked by the abnormal appearance of histiocytes (macrophages) in the blood. Lipid h., Niemann-Pick disease. Sinus h., a disorder of the lymph nodes in which the distended sinuses are completely or nearly completely, filled by histiocytes, as a result of active multiplication of the littoral cells. H. X, a generic term embracing eosinophilic granuloma, Letterer-Siwe disease and Hand-Schuller-Christian disease and indicating a shared common origin for the three entities. (16 Dec 1997) |
| Letterer-Siwe d. |
a Langerhans cell histiocytosis of early childhood, of autosomal recessive inheritance, characterized by cutaneous lesions resembling seborrheic dermatitis, hemorrhagic tendency, hepatosplenomegaly with lymph node enlargement, and progressive anemia. If untreated it is rapidly fatal. Called also L-S d. and acute disseminated Langerhans cell histiocytosis.
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| Letterer-Siwe disease |
see under disease.
Ãâó: www.mercksource.com/pp/us/cns/cns_health_library.j...
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