| 영문 | gout | 한글 | 통풍 |
|---|---|---|---|
| 설명 | 유전정보를 보관하는 물질인 DNA와 RNA 등을 이루는 핵산은 요산의 형태로 배설이 된다. 이것의 배설에는 여러 가지 효소가 작용한다. 이중에서 HGPRT (Hypoxanthine-Guanine Phosphoribosyl Transferase)라는 효소는 이미 배설이 되려고 요산으로 변환하는 과정의 물질을 다시 핵산으로 바꾸는 작용을 하는 효소이다. 통풍이란 이 HGPRT라는 효소 활성도가 감소되어 발생된다. 이 효소의 활성도가 감소되면 핵산의 배설단계에서 재사용이라는 단계가 없어지므로 과도한 요산의 생성이 있게 된다. 혈중에 과도한 요산이 존재하고 이 요산은 결정을 만들어서 관절 주위 및 연부 조직에 침착되어 격심한 발작성 관절통을 야기하는 급성 염증성 관절염을 일으키는 특징적인 병이다. 또 이 요산의 결정들이 콩팥이나 심장에 축적되어서 콩팥 및 심혈관계에 장애가 발생할 수도 있어 내과적 치료를 요하는 병이다. 유전 양식상 보통염색체 우성으로 유전하는 유전병이다. 보통염색체 우성 유전을 하지만 남자와 여자에서 표현률이 달라서 남자가 95%이상을 차지한다. |
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| 영문 | arthritis | 한글 | 관절염 |
|---|---|---|---|
| 설명 | 관절에 일어난 염증. 원인에 따라 화농성-결핵성-매독성 등 감염성과 류마티스에 의한 것, 외상으로 인한 것 등으로 나눈다. 임상상으로는 급성과 만성으로 나뉜다. 1. 급성. ① 장액관절염: 보통 외상에 의해 일어나며 원인불명의 것도 있으나 대개 하나의 관절에만 발생한다. ② 장액섬유소관절염: 급성관절 류마티스 때에 일어나며, 관절강내에 혼탁한 삼출액이 고인다. 섬유소의 거짓막이 생겨 염증이 가라앉아도 심한 운동장애를 남긴다. ③ 화농관절염: 관절의 개방창 또는 임질-성홍열-패혈증 같은 전염병에 다발성을 보인다. 생후 1~2개월의 유아는 뼈가 심하게 상하여 치료할 수 없는 탈구를 일으킨다. 성인에서는 뼈막골수염에 걸려 화농부가 터져 고름이 관절로 들어가는 것이 많으며, 이를 2차화농관절염이라고 한다. 2. 만성. ① 특수염증: 결핵성-매독성 혹은 중년 이후의 남자에 많은 요산의 대사 장애로 인한 통풍성 관절염이 있다. ② 다발관절염: 만성관절 류마티스에 의한 것이 많으며 급성장액관절염에서 이행한 것과 결핵-매독-임질의 경과 중에 볼 수 있는 다발성 및 패혈증의 하나도 있고, 여기에는 스틸병이라는 관절염도 포함된다. ③ 변형골관절염: 뼈나 관절의 노화 또는 외상이 원인이다. ④ 혈우병괄절염: 혈우병을 앓을 때 관절 내의 출혈에 의한 것이다. |
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| 영문 | rheumatoid arthritis | 한글 | 류마티스관절염 |
|---|---|---|---|
| 설명 | 만성의 관절병으로 보통 여러 관절을 침범하며, 윤활막(관절을 둘러싸고 있으며, 관절의 움직임을 마찰없이 원활하게 수행되도록 함), 관절구조의 염증성 변화와 뼈의 위축과 소모가 두드러진다. 말기에는 변형과 강직이 일어나며 원인은 불명이나 자가면역성 또는 바이러스의 감염에 의한 것으로 생각된다. 치료는 계열의 소염진통제가 사용된다. |
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| PRAGMATIC | pregnancy, rheumatoid arthritis, acromegaly, glucose metabolism disorders, mechanical injury, amyloi... |
|---|---|
| ABCDES | abnormal alignment, bones-periarticular osteoporosis, cartilage-joint space loss, deformities, margi... |
| ABC | absolute basophil count; absolute bone conduction; acalculous biliary colic; acid balance control; a... |
| JRA | Juvenile Rheumatoid Arthritis; 연소기 류마토이드 관절염 = Juvenile Chronic Arthritis; 연소기 만성 관절... |
| RA | 1) Refractory Anemia 2) Rheumatoid Arthritis ? Arthritis 3... |
| AA | Adjuvant induced arthritis |
|---|---|
| AIA | Adjuvant induced arthritis |
| AIA | Antigen induced arthritis |
| A.I.M.S. | Arthritis Impact Measurement Scale |
| AIMS2 | Arthritis Impact Measurement Scale |
acute arthritis
| gout arthritis | <rheumatology> Recurrent acute arthritis of peripheral joints caused by the accumulation of monosodium urate crytals. Often presents as pain and swelling confined to one joint. The big toe joint is commonly affected. The arthritis occurs secondary to an inherited abnormality of purine metabolism, resulting in the deposition of uric acid crystals (sodium urate) within the joint space and articular cartilage. Usually due to overproduction of uric acid but may be a result of under excretion. The problems partly arise because neutrophils release lysosomal enzymes as a result of damage to the phagosome membrane by ingested crystals: colchicine acts to reduce the attack by inhibiting lysosome phagosome fusion. (18 Nov 1997) |
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| arthritis, gout | Joint inflammation caused by uric acid crystal deposits in the joint space An attack is usually extremely painful.The uric acid crystals are deposited in the joint fluid (synovial fluid) and joint lining (synovial lining). Intense joint inflammation occurs as white blood cells engulf the uric acid crystals, causing pain, heat, and redness of the joint tissues. The term gout commonly is used to refer to these painful arthritis attacks but gouty arthritis is only one manifeatation of gout. (12 Dec 1998) |
|---|---|
| calcium gout | <rheumatology> Chondrocalcinosis, chronic recurrent arthritis clinically similar to gout. (27 Sep 1997) |
| masked gout | latent gout |
| retrocedent gout | An obsolete term for the occurrence of severe gastric, cardiac, or cerebral symptoms during an attack of gout, especially when the joint and other symptoms suddenly subside at the same time. Saturnine gout, gout occurring in a person with lead poisoning. Synonym: lead gout. Secondary gout, gout resulting from increased serum uric acid levels as a result of an antecedent disease, such as a proliferative disease of the blood and bone marrow, lead poisoning, or prolonged chronic renal failure (on dialysis). Tophaceous gout, gout in which deposits of uric acid and urates occur as gouty tophi. (05 Mar 2000) |
| gout | <rheumatology> Recurrent acute arthritis of peripheral joints caused by the accumulation of monosodium urate crytals. Often presents as pain and swelling confined to one joint. The big toe joint is commonly affected. The arthritis occurs secondary to an inherited abnormality of purine metabolism, resulting in the deposition of uric acid crystals (sodium urate) within the joint space and articular cartilage. Usually due to overproduction of uric acid but may be a result of under excretion. The problems partly arise because neutrophils release lysosomal enzymes as a result of damage to the phagosome membrane by ingested crystals: colchicine acts to reduce the attack by inhibiting lysosome phagosome fusion. (18 Nov 1997) |
| gout diet | A diet containing a minimal quantity of purine bases (meats); liver, kidney, and sweetbread especially are excluded and replaced by dairy products, fruits, and cereals; alcoholic beverages also are excluded. Synonym: purine-free diet. (05 Mar 2000) |
| gout suppressants | Agents that increase uric acid excretion by the kidney (uricosuric agents), decrease uric acid production (antihyperuricaemics), or alleviate the pain and inflammation of acute attacks of gout. (12 Dec 1998) |
| gout, tophaceous | A form of chronic gout. Nodular masses of uric acid crystals (tophi) are deposited in different soft tissue areas of the body. Even though tophi are most commonly found as hard nodules around the fingers, at the tips of the elbows, and around the big toe, tophi nodules can appear anywhere in the body. They have been reported in unexpected areas such as in the ears, vocal cords, or around the spinal cord! (12 Dec 1998) |
| primary gout | Acute episodes of crystal-induced synovitis due to abnormality of purine metabolism; lower than normal urinary excretion of urate leading to hyperuricaemia and acute episodes of joint inflammation. Synonym: primary gout. Interval gout, an asymptomatic phase between acute attacks of gout. Latent gout, hyperuricaemia without symptoms of gout. Often used synonymously with interval gout. Synonym: masked gout. (05 Mar 2000) |
| idiopathic gout | Acute episodes of crystal-induced synovitis due to abnormality of purine metabolism; lower than normal urinary excretion of urate leading to hyperuricaemia and acute episodes of joint inflammation. Synonym: primary gout. Interval gout, an asymptomatic phase between acute attacks of gout. Latent gout, hyperuricaemia without symptoms of gout. Often used synonymously with interval gout. Synonym: masked gout. (05 Mar 2000) |
| tophaceous gout | Nodular masses of uric acid crystals (tophi) are deposited in different soft tissue areas of the body. Even though tophi are most commonly found as hard nodules around the fingers, at the tips of the elbows, and around the big toe, tophi nodules can appear anywhere in the body. They have been reported in unexpected areas such as in the ears, vocal cords, or around the spinal cord! tophaceous gout is always a result of chronic gout. (12 Dec 1998) |
| lead gout | saturnine gout |
| acute rheumatic arthritis | Arthritis due to rheumatic fever. (05 Mar 2000) |
| arthritis | <rheumatology> An inflammatory condition that affects joints. Can be infective, autoimmune, traumatic in origin. Origin: Gr. Arthron = joint (18 Nov 1997) |
| arthritis, adjuvant | An arthritis experimentally induced in animals with freund's adjuvant. (12 Dec 1998) |
제품명 |
판매사 |
보험코드 | 성분/함량 | 구분/보험급여 |
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제품명 |
판매사 |
보험코드 | 성분/함량 | 구분/보험급여 |
|---|