| cosmid | <molecular biology> An artificially constructed type of bacteriophage lambda cloning vector containing the cos gene of phage lambda. Cosmids can be packaged in lambda phage particles for infection into E. Coli, this permits cloning of larger DNA fragments (up to 45 kb) than can be introduced into bacterial hosts in plasmid vectors. They are used as cloning vehicles for the study of aberrant eukaryotic structural genes and also as genetic vectors for introducing the nucleic acid of transforming viruses into cultured cells. Often used for construction of genomic libraries, because of their ability to carry relatively long pieces of DNA insert, compared with plasmids. (04 Jul 1999) |
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| cosmid map | <molecular biology> A physical map that includes a collection of bacteria containing cosmids that carry the DNA fragments under study. (10 Nov 1998) |
Synonyms : Cosmid
| cosmid |
A plasmid vector which contains the two cos (cohesive) ends of phage lambda (l) and one or more selectable markers such as an antibiotic resistance gene. Cosmids exploit certain properties of phage lambda (l) to enable large, 40-50 kb, DNA fragments to be cloned at high efficiency. Cosmids and cosmid recombinants replicate as plasmids.
Ãâó: www.fao.org/docrep/003/X3910E/X3910E06.htm
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| cosmid |
A hybrid plasmid that contains cos sites at each end. Cos sites are recognized during head filling of lambda phages. Cosmids are useful for cloning large segments of foreign DNA (up to 50 kb).
Ãâó: helios.bto.ed.ac.uk/bto/glossary/c2.htm
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| cosmid |
A plasmid into which has been inserted the cos site of bacteriophage. (16)
Ãâó: ppathw3.cals.cornell.edu/glossary/Defs_C.htm
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| cosmid |
A cloning vector derived from a bacterial virus. It can accommodate about 40 kb of inserted DNA.
Ãâó: www.bscs.org/onco/glossary.htm
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| cosmid |
Artificially constructed cloning vector containing the cos gene of phage lambda. Cosmids can be packaged in lambda phage particles for infection into E. coli; this permits cloning of larger DNA fragments (up to 45 kb) than can be introduced into bacterial hosts in plasmid vectors.
Ãâó: www.bioinformatics.buffalo.edu/current_buffalo/glo...
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