| BRCA1 | <molecular biology> BRCA1 is a tumour-supressing gene, if even one copy of it is damaged, cancer can develop. Certain mutations confer a high probability (85% lifetime risk) of developing breast cancer, and other types cause ovarian cancer. Familial mutations of this gene are particularly common among people in the Ashkenazi Jewish ethnic group. (09 Oct 1997) |
|---|---|
| BRCA1 breast cancer susceptibility gene | This mutated (changed) version of the BRCA1 gene makes a person susceptible to developing breast cancer. (12 Dec 1998) |
| BRCA1 protein | Phosphoprotein encoded by the BRCA1 gene (genes, BRCA1). It has limited sequence similarity with known proteins. In normal cells the BRCA1 protein is localised in the nucleus, whereas in the majority of breast cancer cell lines and in malignant pleural effusions from breast cancer patients, it is localised mainly in the cytoplasm. (science 1995;270(5237):713,789-91) (12 Dec 1998) |
| genes, BRCA1 | Tumour suppressor genes located on human chromosome 17q12-21. The mutation of these genes is associated with the formation of familial breast and ovarian cancer. (12 Dec 1998) |
|---|
Synonyms : Breast Cancer 1 Protein
| BRCA1 |
A gene that normally helps to restrain cell growth.
Ãâó: aspin.asu.edu/geneinfo/glos-b.htm
|
|---|---|
| BRCA1 |
A mutation in the BRCA1 gene confers an 85% chance of developing breast cancer during a woman
Ãâó: www.vh.org/adult/patient/cancercenter/prevention/p...
|
| BRCA1 |
A gene located on chromosome 17 that normally helps to suppress cell growth. Inheriting an altered version of BRCA1 predisposes an individual to breast, ovarian, or prostate cancer.
Ãâó: www.spineuniverse.com/community/cancerdictionary.h...
|
| BRCA1 |
A tumor suppressor gene, the breast cancer 1 susceptibility gene is known to play a role in repairing DNA breaks. Mutations in this gene are associated with increased risks of developing breast or ovarian cancer.
Ãâó: www.jco.org/cgi/glossarylookup
|
| BRCA1 |
a gene which, when damaged (mutated), places a woman at greater risk of developing breast and/or ovarian cancer, compared with women who do not have the mutation. In a woman with a BRCA1 mutation, the estimated lifetime risk of developing breast cancer is about 50% compared with 12% in the general population. A person who has this mutated gene has a 50% chance of passing on the gene to each of her children. ...
Ãâó: www.cancer.org/docroot/GRY/GRY_0.asp
|
Á¦Ç°¸í |
ÆÇ¸Å»ç |
º¸ÇèÄÚµå | ¼ººÐ/ÇÔ·® | ±¸ºÐ/º¸Çè±Þ¿© |
|---|
Á¦Ç°¸í |
ÆÇ¸Å»ç |
º¸ÇèÄÚµå | ¼ººÐ/ÇÔ·® | ±¸ºÐ/º¸Çè±Þ¿© |
|---|