| HYP | hydroxyproline; hypnosis |
|---|---|
| Hyp | hydroxyproline; hyperresonance; hypertrophy; hypothalamus |
| Hypro | hydroxyproline |
| OHP | hydroxyprogesterone; hydroxyproline; occupational health plan; Oregon Health Plan; oxygen under high... |
| THP | Tamm-Horstall protein; tetrahydropapaveroline; tissue hydrostatic pressure; total hip replacement; t... |
| HYP | 3-hydroxyproline |
|---|---|
| CHP | Cis-4-hydroxyproline |
| HP | Hydroxyproline |
| HyPRO | Hydroxyproline |
| HRGP | Hydroxyproline rich glycoprotein |
| hydroxyproline | Specific proline residues on the amino side of a glycine residue in collagen become hydroxylated at C4, before the polypeptides become helical, by the activity of prolyl hydroxylase. This enzyme has a ferrous ion at the active site and a reducing agent such as ascorbate is necessary to maintain the iron in the ferrous state. The presence of hydroxyproline is essential to produce stable triple helical tropocollagen, hence the problems caused by ascorbate deficiency in scurvy. This unusual amino acid is also present in considerable amounts in the major glycoprotein of primary plant cell walls (see HRGP). (18 Nov 1997) |
|---|---|
| hydroxyproline oxidase | <enzyme> Oxidises 4-hydroxy-l-proline to delta'-pyrroline-3-hydroxy-5-carboxylate Registry number: EC 1.5.99.- (26 Jun 1999) |
| hydroxyproline rich glycoprotein | See: HRGP. (18 Nov 1997) |
| arabinosyl-hydroxyproline transferase | <enzyme> Involved in glycoprotein synthesis in plants Registry number: EC 2.4.2.- Synonym: ar-hpt, protein-arabinosyltransferase (26 Jun 1999) |
|---|---|
| 3-hydroxyproline | A derivative of proline found in certain collagens, particularly basement membrane collagen. Synonym: 3-hydroxy-2-pyrrolidinecarboxylic acid. (05 Mar 2000) |
| 4-hydroxyproline | 4-Hydroxy-2-pyrrolidinecarboxylic acid;the trans-l-isomer is an imino acid found among the hydrolysis products of collagen; not found in proteins other than those of connective tissue. A vitamin C deficiency will result in impaired formation of hydroxyproline. (05 Mar 2000) |
| 4-hydroxyproline oxidase | A flavoenzyme that catalyses the conversion of 4-hydroxyproline to d'-pyrroline-3-hydroxy-5-carboxylate using FAD; this enzyme appears to be deficient in individuals with hyperhydroxyprolinaemia, an enzyme that catalyses the reaction of 4-hydroxyproline with NAD+ to form NADH and 4-oxoproline. Synonym: 4-oxoproline reductase. (05 Mar 2000) |
Synonyms : 4-Hydroxyproline, cis-4-Hydroxyproline, 4 Hydroxyproline, cis 4 Hydroxyproline
| hydroxyproline |
a crystalline amino acid obtained from gelatin or collagen
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| hydroxyproline oxidase |
an enzyme of the oxidoreductase class that catalyzes the oxidation of 4-hydroxyproline to form the 3-hydroxy analog of Δ1-pyrroline 5-carboxylate as part of the pathway of degradation of free hydroxyproline. Deficiency of the enzyme, an autosomal recessive trait, results in hydroxyprolinemia.
Ãâó: www.mercksource.com/pp/us/cns/cns_health_library.j...
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| hydroxyprolinemia |
1. excess of hydroxyproline in the blood. 2. an autosomal recessive aminoacidopathy characterized by an excess of free hydroxyproline in the plasma and urine, due to a defect in the enzyme hydroxyproline oxicase; it may be associated with mental retardation. Called also hyperhydroxyprolinemia.
Ãâó: www.mercksource.com/pp/us/cns/cns_health_library.j...
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| hydroxyproline | a crystalline amino acid obtained from gelatin or collagen |
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