| ILP | inadequate luteal phase; insufficiency of luteal phase; interstitial laser photocoagulation; interst... |
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| SPIA | solid-phase immunoabsorption; solid-phase immunoassay |
| LPD | Luteal Phase Defect |
| AP | accessory pathway; accounts payable; acid phosphatase; acinar parenchyma; action potential; active p... |
| APP | acute phase protein; alum-precipitated pyridine; aminopyrazolopyrimidine; amyloid peptide precursor;... |
| Phase I | phase |
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| S phase | synthesis phase |
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| APRF | 3/acute phase response factor |
| SPRIA | Solid Phase Radioimmune Assay |
| APR | Acute Phase Response |
| APP | Acute phase proteins |
| phase | Any one of the varying aspects or stages through which a disease or process may pass. Origin: Gr. Phasis = an appearance (18 Nov 1997) |
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| phase angle | <microscopy> The angular equivalent of the time displacement between corresponding points on two sine waves of the same frequency. (05 Aug 1998) |
| phase contrast | <microscopy> An optical method devised by F. Zernike for converting the focused image of a phase object (one with differences in refractive index or optical path but not in absorbance), which ordinarily is not visible in focus, into an image with good contrast. (05 Aug 1998) |
| phase contrast microscopy | <investigation> A simple nonquantitative form of interference micoscopy of great utility in visualising live cells. Small differences in optical path length due to differences in refractive index and thickness of structures are visualised as differences in light intensity. (18 Nov 1997) |
| phase encoding | In magnetic resonance imaging, the technique of inducing a gradient in the magnetic field in the Y-axis to induce phase differences with location. Synonym: gradient encoding. (05 Mar 2000) |
| phase I block | Inhibition of nerve impulse transmission across the myoneural junction associated with depolarisation of the motor endplate, as in the muscle paralysis produced by succinylcholine. (05 Mar 2000) |
| phase I clinical trial | <pharmacology> The earliest stage clinical trial for studying an experimental drug in humans. Phase I trials are generally comparatively small and are used to determine toxicity and maximum dose. They provide an initial evaluation of a drug's safety and pharmacokinetics-how the drug is absorbed, what tissues it reaches and how long it takes to leave the body. Such studies also usually test various doses of the drug (dose-ranging) to obtain an indication of the appropriate dose to use in later studies. The patients in these trials usually have advanced disease and have already received best available chemotherapy, therefore, seeing a repose is significant partially because this means there is a lack of cross-resistance between two anti-cancer drugs. (31 Dec 1997) |
| phase II block | Inhibition of nerve impulse transmission across the myoneural junction unaccompanied by depolarisation of the motor endplate, as in the muscle paralysis produced by tubocurarine. (05 Mar 2000) |
| phase II clinical trial | <pharmacology> Usually focus on the activity of the new product as a single agent in a noncomparative, open study. (31 Dec 1997) |
| phase III clinical trial | <pharmacology> An advanced stage clinical trial that should conclusively show how well a drug works as compared to other treatments. Phase III trials are large, frequently multi-institution tests. They generally compare the relative value of the new drug compared with the current standard treatment and measure whether a new drug extends survival or otherwise improves the health of patients on treatment (clinical improvement) rather than just provide surrogate marker data. These studies generally last longer and are larger than phase II trials. (31 Dec 1997) |
| phase image | A magnetic resonance image showing only phase shift information, to detect motion. (05 Mar 2000) |
| phase plate | <microscopy> The plate used near the back focal plane of a microscope objective lens (in conjunction with an annulus at the front focal plane of the condenser lens) to achieve phase contrast. The phase plate selectively shifts the phase of the waves diffracted by the specimen by a quarter wave and reduces the amplitude of the undeviated, direct beam. (05 Aug 1998) |
| phase rule | An expression of the relationships existing between systems in equilibrium: P + V = C + 2, where P is the number of phases, V the variance or degrees of freedom, and C the number of components; it also follows that the variance is, V = C + 2 -P. For H2O at its triple point, V = 1 + 2 -3 = 0, i.e., both temperature and pressure are fixed. Synonym: Gibb's phase rule. (05 Mar 2000) |
| phase separation | <chemistry> The separation of fluid phases that contain different concentrations of common components. Occurs with partially miscible solvents used in many biochemical separation methods. Also temperature dependent phase separation occurs with some detergent solutions. With reference to membranes means the segregation of lipid components into domains that have different chemical composition. (31 Dec 1997) |
| phase shift | <microscopy> A change in the phase relationship between two alternating quantities of the same frequency. (05 Aug 1998) |
| accelerated phase of leukaemia | Refers to chronic myelogenous leukaemia that is progressing. The number of immature, abnormal white blood cells in the bone marrow and blood is higher than in the chronic phase, but not as high as in the blast phase. (12 Dec 1998) |
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| acceleration phase | <cell biology, cell culture> A period of increasing growth before the log phase in a culture of microbes. After the culture is started on a medium, at first there is no growth (the lag phase) and then the microbes start to gradually grow (acceleration phase) until they reach a constant maximum rate of growth (log phase). (15 Jan 1998) |
| acute-phase protein | <haematology> These plasma proteins (in addition to fibrinogen) increase 25% or more in response to inflammation and injury are under direct control of interleukin-6 (IL-6) (hepatocyte-stimulating factor). Other proteins which increase are ceruloplasmin, C3 and C4 which increase 50% or more; alpha-1 acid glycoprotein, alpha-1 antitrypsin, haptoglobin and fibrinogen (the major determinant of viscosity 1 ) which increase two- to fourfold; C-reactive protein (CRP) and serum amyloid A which increase several hundred-fold. Despite long-held clinical opinion to the contrary, available data indicate that neither ESR nor measurement of specific acute-phase reactants are useful in excluding underlying infection or inflammation regardless of the pretest probability. These proteins are secreted into the blood in increased or decreased quantities by hepatocytes in response to trauma, inflammation, or disease. They can serve as inhibitors or mediators of the inflammatory processes. Certain acute-phase proteins have been used to diagnose and follow the course of diseases or as tumour markers. See also: amyloid, c-reactive protein, erythrocyte sedimentation rate, viscosity. (25 Jun 1999) |
| acute-phase reaction | <immunology, rheumatology> Refers to the changes in synthesis of certain proteins within the serum during an inflammatory response, which provides rapid protection for the host against microorganisms via non-specific defense mechanisms. It consists of fever, an increase in inflammatory humoral factors, and an increased synthesis by hepatocytes of a number of proteins or glycoproteins usually found in the plasma; the reaction is mediated by endogenous pyrogens, the hypothalamus, adrenal hormones, and other factors. (12 Jul 2000) |
| anal phase | In psychoanalytic personality theory, the stage of psychosexual development, occurring when a child is between 1 and 3 years, during which activities, interests, and concerns are centreed around the anal zone. (05 Mar 2000) |
| aqueous phase | The water portion of a system consisting of two liquid phase's, one mainly water, the other a liquid immiscible with water (e.g., benzene, ether). (05 Mar 2000) |
| blast phase | Refers to advanced chronic myelogenous leukaemia. In this phase, the number of immature, abnormal white blood cells in the bone marrow and blood is extremely high. Also called blast crisis. (12 Dec 1998) |
| g0 phase | Phase of the cell cycle where cells exist in a quiescent state. These cells have unduplicated DNA, degraded RNA and protein, and low enzyme activity. The ability to switch between g0 and g1 (and vice versa) determines the post-embryonic cell proliferation rate and is defectively controlled in neoplastic cells. (12 Dec 1998) |
| g1 phase | <cell biology, molecular biology> The period during interphase in the cell cycle between mitosis and the S phase (when DNA is replicated). Also known as the decision period of the cell, because the cell decides to divide when it enters the s phase. The G stands for gap. (09 Oct 1997) |
| g2 phase | <cell biology, molecular biology> The period during interphase in the cell cycle between the S phase (when DNA is replicated) and mitosis (when the nucleus, then cell, divides). at this time, the cell checks the accuracy of DNA replication and prepares for mitosis. The G stands for gap. (09 Oct 1997) |
| radial growth phase | The early pattern of growth of cutaneous malignant melanoma, in which tumour cells spread laterally in the epidermis. (05 Mar 2000) |
| Gap1 phase | The period of the cell cycle after cell division when there is synthesis of RNA and protein; it may last for a few hours in rapidly growing tissue or a lifetime in non-renewing cells such as nerve cells. Synonym: Gap1 phase, postmitotic phase. (05 Mar 2000) |
| Gap2 phase | The period in the cell cycle when synthesis of DNA is completed but before mitosis begins. Synonym: Gap2 phase, premitotic phase. (05 Mar 2000) |
| genital phase | In psychoanalytic personality theory, the final stage of psychosexual development, occurring during puberty, in which the individual's psychosexual development is so organised that sexual gratification can be achieved from genital-to-genital contact and the capacity exists for a mature affectionate relationship with an individual of the opposite sex. See: phallic phase. (05 Mar 2000) |
| vertical growth phase | Spread of melanoma cells from the epidermis into the dermis and later the subcutis, from which site metastasis may take place. (05 Mar 2000) |
Synonyms : Gas-Liquid-Solid Phase Transitions, Sol-Gel Phase Transition, Gas Liquid Solid Phase Transitions, Gas-Liquid-Solid Phase Transition, Phase Transition, Gas-Liquid-Solid, Phase Transition, Sol-Gel, Phase Transitions, Phase Transitions, Gas-Liquid-Solid
Synonyms : Phaseolus acutifolius, Phaseolus vulgaris
| phase |
(physical chemistry) a distinct state of matter in a system; matter that is identical in chemical composition and physical state and separated from other material by the phase boundary; "the reaction occurs in the liquid phase of the system" any distinct time period in a sequence of events; "we are in a transitional stage in which many former ideas must be revised or rejected" arrange in phases or stages; "phase a withdrawal" a particular point in the time of a cycle; measured from some arbitrary zero and expressed as an angle (astronomy) the particular appearance of a body's state of illumination (especially one of the recurring shapes of the part of Earth's moon that is illuminated by the sun); "the full phase of the moon" adjust so as to be in a synchronized condition; "he phased the intake with the output of the machine"
Ãâó: wordnet.princeton.edu/perl/webwn
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| Phaseolus |
herbs of warm regions including most American beans
Ãâó: wordnet.princeton.edu/perl/webwn
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| phase |
In the physical sciences, a phase is a set of states of a macroscopic physical system that have relatively uniform chemical composition and physical properties (i.e. density, crystal structure, index of refraction, and so forth.) The most familiar examples of phases are solids, liquids, and gases. ...
Ãâó: en.wikipedia.org/wiki/Phase_(matter)
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| phase I trial |
The first step in testing a new treatment in humans. These studies test the best way to give a new treatment (for example, by mouth, intravenous infusion, or injection) and the best dose. The dose is usually increased a little at a time in order to find the highest dose that does not cause harmful side effects. ...
Ãâó: www.stjude.org/glossary
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| phase II trial |
A study to test whether a new treatment has an anticancer effect (for example, whether it shrinks a tumor or improves blood test results) and whether it works against a certain type of cancer.
Ãâó: www.stjude.org/glossary
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| phase | (astronomy) the particular appearance of a body's state of illumination (especially one of the recurring shapes of the part of Earth's moon that is illuminated by the sun) |
|---|---|
| phase | (physical chemistry) a distinct state of matter in a system |
| phase | a particular point in the time of a cycle |
| phase | any distinct time period in a sequence of events |
| phase | adjust so as to be in a synchronized condition |
| phase | arrange in phases or stages |
| phase | a particular point in the time of a cycle |
| phase | a change from one state (solid or liquid or gas) to another without a change in chemical composition |
| phase | a clinical trial on a few persons to determine the safety of a new drug or invasive medical device |
| phase | a clinical trial on a few persons to determine the safety of a new drug or invasive medical device |
| phase | a clinical trial on more persons than in phase I |
| phase | a clinical trial on more persons than in phase I |
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