| 영문 | amyloidosis | 한글 | 아밀로이드증 |
|---|---|---|---|
| 설명 | 본래 생체에는 없는 당단백질의 일종으로 비정상적으로 아밀로이드단백이 조직이나 장기에 침착되는 병. 발현부위가 전신성인 경우의 아밀로이드증(전신성 아밀로이드증)에는 명백한 원인없이 일어나는 원발성 아밀로드증과 만성화농성 염증이나 결핵 등 소모성 질환에서 찾아볼 수 있는 속발성 아밀로이드증이 있다. 발현부위가 국소성인 경우의 국소성 아밀로이드증으로서는 뇌의 노인반이 그 예이며, 특히 입안에서는 혀나 잇몸에 대한 침착이 현저하고 여러 가지 기능장애를 나타낸다. 조직학적으로는 헤마톡실린 에오진염색에서는 에오진성 무구조인 유리화를 나타내며 콩고레드, 편광상(녹색) 등으로 확인한다. 구조적으로는 아밀로이드 섬유의 집합으로 이루어지는 여러 가지 아밀로이드 침착이 있으며 그것들에 대한 병형이 분류되어 있다. 가족형, 다발성 골수종과 수반하는 형 그리고 가족성 지중해열을 수반하는 형 등이 있다. |
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| APP | acute phase protein; alum-precipitated pyridine; aminopyrazolopyrimidine; amyloid peptide precursor;... |
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| AA | 1) Aortic Arch(= Arcus Aortae)(= AA); 대동맥궁 2) Aplastic Anemia - Anemia |
| AEF | Amyloid Enhancing Factor |
| AH | 1) Atrial Hypertrophy 2) Anti-Hyaluronidase 3) Amyloid imm... |
| AL | Amyloid immunoglobulin Light chain protein |
| A beta | AD beta-amyloid |
|---|---|
| AA | Amyloid A |
| AA | Amyloid A protein |
| AP | Amyloid P component |
| APP | Amyloid Precursor Protein |
| amyloid | Glycoprotein deposited extracellularly in tissues in amyloidosis. The glycoprotein may either derive from light chain of immunoglobulin (AIO (amyloid of immune origin): 5-18 kD glycoprotein, product of a single clone of plasma cells, the N terminal part of lambda or kappa light chain) or, in what used to be referred to as AUO, amyloid of unknown origin, from serum amyloid A (SAA), one of the acute phase proteins that increases many fold in inflammation. The polypeptides are organised as a _ pleated sheet making the material rather inert and insoluble. Minor protein components are also found. Should be distinguished from _ amyloid deposited in the brain and that is derived from amyloid precursor protein (see amyloidogenic glycoprotein. (18 Nov 1997) |
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| amyloid A-degrading serine protease | <enzyme> Reduced in amyloidosis associated with rheumatoid arthritis Registry number: EC 3.4.21.- Synonym: amyloid a-degrading activity, aad-protease (26 Jun 1999) |
| amyloid angiopathy | Deposition of acellular hyaline material in small arteries and arterioles of the leptomeninges and cerebral cortex in the elderly with resulting predilection for recurrent lobar intraparenchymal haematomas. (05 Mar 2000) |
| amyloid beta-protein | A 4 kD protein, 39-43 amino acids long, expressed by a gene located on chromosome 21. It is the major protein subunit of the vascular and plaque amyloid filaments in individuals with alzheimer's disease and in aged individuals with trisomy 21 (down syndrome). The protein is found predominantly in the nervous system, but there have been reports of its presence in non-neural tissue. (12 Dec 1998) |
| amyloid beta-protein precursor | A precursor to the amyloid-beta protein (beta/a4). Alterations in the expression of the amyloid beta-protein precursor (abpp) gene, located on chromosome 21, plays a role in the development of the neuropathology common to both alzheimer disease and down syndrome. Abpp is associated with the extensive extracellular matrix secreted by neuronal cells. Upon cleavage, this precursor produces three proteins of varying amino acid lengths: 695, 751, and 770. The beta/a4 (695 amino acids) or beta-amyloid protein is the principal component of the extracellular amyloid in senile plaques found in alzheimer disease, down syndrome and, to a limited extent, in normal aging. (12 Dec 1998) |
| amyloid bodies of the prostate | An obsolete term for small masses of colloid material often present in the tubules of the gland. See: corpus amylaceum. (05 Mar 2000) |
| amyloid corpuscle | One of a number of small ovoid or rounded, sometimes laminated, bodies resembling a grain of starch and found in nervous tissue, in the prostate, and in pulmonary alveoli; of little pathological significance, and apparently derived from degenerated cells or proteinaceous secretions. Synonym: amniotic corpuscle, amylaceous corpuscle, amyloid corpuscle, colloid corpuscle. (05 Mar 2000) |
| amyloid degeneration | Infiltration of amyloid between cells and fibres of tissues and organs. Synonym: waxy degeneration. (05 Mar 2000) |
| amyloid kidney | A kidney in which amyloidosis has occurred, usually in association with some chronic illness such as multiple myeloma, tuberculosis, osteomyelitis, or other chronic suppurative inflammation; such kidney's are moderately enlarged and grossly manifest a waxy appearance, with amyloid deposited beneath the endothelium in the glomerular loops and in the arterioles, apparently beginning as foci of thickening of the basement membranes. Synonym: waxy kidney. (05 Mar 2000) |
| amyloid nephrosis | The nephrotic syndrome due to deposition of amyloid in the kidney. See: renal amyloidosis. (05 Mar 2000) |
| amyloid neuropathies | Disorders of the peripheral nervous system associated with deposition of amyloid. Amyloid neuropathies may result from non-hereditary or hereditary amyloidosis. Several different forms of familial amyloid neuropathies have been described, most of which have specific mutations in the prealbumin gene. (12 Dec 1998) |
| amyloid p component | Amyloid p component is a small, non-fibrillar glycoprotein found in normal serum and in all amyloid deposits. It has a pentagonal (pentaxin) structure. It acts as an acute phase protein in the mouse, modulates immunologic responses in man, inhibits elastase, and has been suggested as an indicator of liver disease. (12 Dec 1998) |
| amyloid precursor protein | <protein> Individuals with Alzheimer's disease are characterised by extensive accumulation of amyloid in the brain, referred to as senile plaques. These consist of a core of amyloid fibrils surrounded by dystrophic neurites. The principal component of the amyloid fibrils is B/A4, a peptide derived from the larger APP. The specific role of amyloid protein is unclear but it is thought that amyloid deposits may cause neurons to degenerate. Amyloid deposits also occur in brains of older Down's Syndrome patients. (04 May 1997) |
| amyloid protein | Glycoprotein deposited extracellularly in tissues in amyloidosis. The glycoprotein may either derive from light chain of immunoglobulin (AIO (amyloid of immune origin): 5-18 kD glycoprotein, product of a single clone of plasma cells, the N terminal part of lambda or kappa light chain) or, in what used to be referred to as AUO, amyloid of unknown origin, from serum amyloid A (SAA), one of the acute phase proteins that increases many fold in inflammation. The polypeptides are organised as a _ pleated sheet making the material rather inert and insoluble. Minor protein components are also found. Should be distinguished from _ amyloid deposited in the brain and that is derived from amyloid precursor protein (see amyloidogenic glycoprotein. (18 Nov 1997) |
| amyloid protein aa | A nonimmunoglobulin amyloid isolated from amyloid fibrils deposited in amyloidosis secondary to chronic inflammatory diseases such as rheumatoid arthritis. Antisera to amyloid protein aa have been used to detect a related serum protein saa. (12 Dec 1998) |
| beta-amyloid | <protein> The protein which forms thick deposits, or plaques, in the brains of people with Alzheimer's disease, a disease where memory skills gradually deteriorate with age. (13 Nov 1997) |
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| cerebral amyloid angiopathy | <pathology> A condition where there is a deposition of amyloid (insoluble protein) in the walls of the arteries which supply the brain. This results in an increased risk of dementia and-or intracerebral haemorrhage. Cerebral amyloidosis or cerebral amyloid angiopathy, is a complication of primary amyloidosis. Origin: Gr. Pathos = disease (27 Sep 1997) |
| serum amyloid | In secondary amyloidosis the fibrils deposited in tissues are unrelated to immunoglobulin light chains (in contrast to the situation in primary amyloidosis) and are made of amyloid A protein (AA protein). This is derived from serum amyloid A (SAA) that is the apolipoprotein of a high density lipoprotein and an acute phase protein. Partial proteolysis converts SAA into the pleated sheet configuration of the amyloid fibrils. Amyloid P protein is also found as a minor component of the fibrils (in both primary and secondary amyloidosis) and is derived from serum amyloid P that has similarity to C-reactive protein. The physiological role remains obscure. (18 Nov 1997) |
| serum amyloid P component | Precursor of amyloid component P, found in basement membrane. Member of the pentraxin family. See: serum amyloid. (18 Nov 1997) |
| islet amyloid peptide | <hormone, protein> Peptide of 37 amino acids that selectively inhibits insulin stimulated glucose uptake in muscle. Structurally related to calcitonin gene-related peptide. (15 Oct 1997) |
| familial amyloid neuropathy | <neurology> A disorder in which various peripheral nerves are infiltrated with amyloid and their functions disturbed, an abnormal prealbumin is also formed and is present in the blood; characteristically, it begins during mid-life and is found largely in persons of Portuguese descent. Other rare clinical types occur. Inheritance: autosomal dominant. Synonym: familial amyloidosis, hereditary amyloidosis. (05 Mar 2000) |
Synonyms : Amyloid Fibrils, Amyloid Proteins, Amyloid Substance, Fibrils, Amyloid, Proteins, Amyloid, Substance, Amyloid
Synonyms : ABP (Alzheimer's), Amyloid AD-AP, AD-AP, Amyloid, Alzheimer beta Protein, Amyloid AD AP, Amyloid beta Protein, Protein A4, Amyloid, Protein, beta-Amyloid, beta Amyloid Protein, beta-Protein, Alzheimer, beta-Protein, Amyloid
Synonyms : Amyloid beta Precursor Protein, Amyloid beta Protein Precursor, beta Amyloid Protein Precursor, beta-Protein Precursor, Amyloid
Synonyms : Amyloid Neuropathy, Secondary, Amyloid Polyneuropathies, Amyloid Neuropathies, Secondary, Amyloid Neuropathy, Amyloid Polyneuropathy, Neuropathies, Secondary Amyloid, Neuropathy, Amyloid, Neuropathy, Secondary Amyloid, Polyneuropathies, Amyloid
Synonyms : Amyloid Polyneuropathy, British Type, Amyloid Polyneuropathy, Iowa Type, Amyloid Polyneuropathy, Swiss Type, Appalachian Type Familial Amyloid Polyneuropathy, British Type Amyloid Polyneuropathy, Familial Amyloid Neuropathy, Andrade Type
| amyloid |
a non-nitrogenous food substance consisting chiefly of starch; any substance resembling starch (pathology) a waxy translucent complex protein resembling starch that results from degeneration of tissue starchlike: resembling starch
출처: wordnet.princeton.edu/perl/webwn
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| amyloidosis |
a disorder characterized by deposit of amyloid in organs or tissues; often secondary to chronic rheumatoid arthritis or tuberculosis or multiple myeloma
출처: wordnet.princeton.edu/perl/webwn
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| amyloid A protein |
a pathological fibrillar low-molecular-weight protein occurring in reactive systemic amyloidosis and familial Mediterranean fever; it is antigenically related to the high-molecular-weight serum amyloid A (SAA) protein. Called also AA p. See also amyloid (def. 3).
출처: www.mercksource.com/pp/us/cns/cns_hl_dorlands.jspz...
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| amyloid light chain protein |
a pathological fibrillar low-molecular-weight protein occurring in immunocyte-derived amyloidosis; it is structurally and immunologically similar to the variable region of either the kappa chains or the lambda chains of immunoglobulins. Called also AL p. See also amyloid (def. 3).
출처: www.mercksource.com/pp/us/cns/cns_hl_dorlands.jspz...
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| amyloid polyneuropathy |
polyneuropathy caused by amyloidosis; symptoms may include dysfunction of the autonomic nervous system, carpal tunnel syndrome, and sensory disturbances in the extremities such as numbness, hyperesthesia, or paresthesia. See also familial amyloid p.
출처: www.mercksource.com/pp/us/cns/cns_hl_dorlands.jspz...
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| amyloid | (pathology) a waxy translucent complex protein resembling starch that results from degeneration of tissue |
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| amyloid | a nonnitrogenous food substance consisting chiefly of starch |
| amyloid | resembling starch |
| amyloid | a plaque consisting of tangles of amyloid protein in nervous tissue (a pathological mark of Alzheimer's disease) |
| amyloid | a plaque consisting of tangles of amyloid protein in nervous tissue (a pathological mark of Alzheimer's disease) |
| amyloid | resembling starch |
| amyloid | a disorder characterized by deposit of amyloid in organs or tissues |
제품명 |
판매사 |
보험코드 | 성분/함량 | 구분/보험급여 |
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제품명 |
판매사 |
보험코드 | 성분/함량 | 구분/보험급여 |
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