안녕하세요?

제가 궁금한 건 다름이 아니라.. GBS에서 patho를 보면 stage가 있던데요..

stage 마지막 단계는 axon까지 손상을 입던데...

Ⅰ. Lymphocytes migrate through endoneural vesseles and surround nerve fiber, but myelin
     sheath and axon not yet danaged.
Ⅱ. More lymphocytes extruded and macrophages appear.
     Segmental demyelination begins, but axon not yet affected.
Ⅲ. Multifocal myelin sheath and axonal damage.
     Central chromatolysis of nerve cell body occurs and muscle begins to develop devervation
     atrophy.
Ⅳ. Extensive axonal destruction. some nerve cell bodies irreversibly damaged, but function may
     be preserved because of adjacent less - affected nerve fibers.



각 단계마다 증상이 어떤 건지 알려 주실 수 있으신지..

또 증상이 나타나는 건 neuron에서 demyelination이 되어야만 나타나는 겁니까?

여러가지로 질문했는데.. 부탁드립니다!!